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A unique resin enabling the pharmaceutical industry to quickly develop and bring new complex peptide drugs candidates to market. Kommunen raddar hif fran konkurs overcomes the challenges of synthesizing longer and more complex therapeutic peptides.

Peptides produced with ChemMatrix have higher purity and can be obtained with better yield. ChemMatrix resin is made exclusively from primary ether bonds which are highly chemically stable. Available on request, ChemMatrix resin can be supplied with an extensive range of linkers for peptide acids, amides and fragments. ChemMatrix resin has been field proven for easier and faster development of long, complex and hydrophobic peptides. Here is an example where both resins were compared for the synthesis of the HIV-1 protease, a 99 amino acid peptide.

Cost-efficient synthesis of long peptides and complex sequences Lower purification costs due to increased crude purity High final recovery yield Faster speed to market for new peptide drugs ChemMatrix Resin Catalog Biotage can supply grams to Kg quantities of the following popular ChemMatrix configurations:.

ChemMatrix resins are designed to be used under identical conditions to polystyrene. The only difference "Kommunen raddar hif fran konkurs" that due to the enhanced solvent and reagent accessibility of the ChemMatrix resin, which gives rise to superior reaction and chemistry performance, the resin may swell more in most solvents including TFA.

The ChemMatrix resins are fully compatable with the Syro family of Biotage peptide instruments. The increased swelling in the case of ChemMatrix confers much greater solvent and reagent accessibility and thereby reduced the occurrence of by products or impurities such as incomplete couplings and deletion sequences.

Please note that the following procedure can be further optimized with alternative coupling agents, depending on the coupling Kommunen raddar hif fran konkurs and requirements, for examples: N,N-diisopropylethylamine can also be replaced by weaker bases such as N-methylmorpholine if racemization is a specific risk to your peptide.

The cleavage step relies on the use of TFA. Depending on the peptide sequence, all kind of cleavage cocktails could be used.

If Arg Pbf is present in the sequence, the cleavage should be left 3 hours instead of one. Biotage has developed a range of tools to improve the peptide synthesis workflow, from synthesis of crude peptides through to the final purified product. These solutions make your workflow more efficient and improve the quality of peptides you synthesize.

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Our workflow solutions are used in pharma, biotech, CRO and academic laboratories throughout the world. Please contact webmaster to add to, or update this page. Let Biotage make orde ChemMatrix offers substantial advantages over traditional PS and P Other amino acids can be preloaded on special request.

This resin therefore Kommunen raddar hif fran konkurs the same cleavage conditions as the Cl-Trityl-polystyrene. On request, Trityl-ChemMatrix resins can be offered preloaded will all 20 natural amino acids. Please take note that the Cl-Trityl-ChemMatrix resin is not offered for stability reasons. It is more effective to start with the Trityl-ChemMatrix resin, chlorinate the resin and then add the amino acid required.

"Kommunen raddar hif fran konkurs" ChemMatrix was the first ChemMatrix resin developed for peptide acids. It remains to this day one of the work-horses for solid phase peptide synthesis SPPS. A Major Advance In Solid Phase Peptide Synthesis A unique resin enabling the pharmaceutical industry to quickly develop and bring new complex peptide drugs candidates to market. Highlighted products Read more News. Exceptional Stability ChemMatrix resin is made exclusively from primary ether bonds which are highly chemically stable.

Superior Properties No leaching occurs during synthesis and cleavage. High Loadings ChemMatrix resins have a loading of 0. Solvent Compatibility ChemMatrix allows the use of almost any kind of solvent, including water. Versatile Choices Available on request, ChemMatrix resin can be supplied with an extensive range of linkers for peptide acids, amides and fragments.

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Demonstrated Superiority ChemMatrix resin has been field proven for easier and faster development of long, complex and hydrophobic peptides. Superior Performance Makes ChemMatrix an Exceptional Value Cost-efficient synthesis of long peptides and complex sequences Lower purification costs due to increased crude purity High final recovery yield Faster speed to market for new peptide drugs ChemMatrix Resin Catalog Biotage can supply grams to Kg quantities of the following popular ChemMatrix configurations: Recommended Protocol — General Advice Please note that the following procedure can be further optimized with alternative coupling agents, depending on the coupling system and requirements, for examples: Log in for hundreds of free application notes and support documents.

Peptide Synthesis Workflow - Synthesis, Purification, and Evaporation Solutions Biotage has developed a range of tools to improve the peptide synthesis workflow, "Kommunen raddar hif fran konkurs" synthesis of crude peptides through Kommunen raddar hif fran konkurs the final purified product.

News Peptide Association Links Relevant peptide associations.

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